低剂量CT灌注在高血压并颈动脉狭窄性短暂性脑缺血发作的应用

目的:探讨低剂量CT脑灌注成像在高血压并颈动脉狭窄性短暂性脑缺血发作(TIA)的应用。方法:选取高血压颈动脉狭窄TIA患者62例,分为实验组、对照组,每组31例,实验组行低剂量辐射、低浓度对比剂进行灌注扫描;对照组常规扫描,获得灌注图像进行分析。结果:实验组与对照组,对不同程度高血压患者脑血流低灌注的检出分别为实验组轻度2例、中度5例、重度7例,对照组为轻度1例、中度8例、重度6例,X^2为0.065,P值为0.799,差异无统计学意义。对不同程度的颈动脉狭窄的病人,脑血流低灌注的检出分别为实验组:轻度2例、中度4例、重度8例、闭塞2例;对照组:轻度0例、中度4例、重度9例、闭塞1例,X^2为0.258,P值为0.611,差异无统计学意义(P>0.05)。结论:应用低剂量CT灌注成像能够准确评估高血压并颈动脉狭窄性TIA的脑组织血流灌注情况,有利于受检者辐射剂量、对比剂用量的减少,同时减少对比剂肾病的发生率。

Object:To explore the application value of hypertension and carotid stenosis TIA by low-dose CT cerebral perfusion imaging.Methods:Select 62 cases of hypertension and carotid stenosis TIA patients,divided into the experimental group and control group,31 cases in each group, experimental group line of low dose radiation and low concentration of contrast agent perfusion scan;The control group conventional scanning, all perfusion images were analyzed.Results:The experimental group and control group, Low cerebral blood flow perfusion in patients with different degree of hypertension in the detection of the experimental group respectively mild 2 cases、moderate 5 cases、severe 7cases, Control group: mild 1 cases、moderate 8 cases、severe 6cases,X^2 is 0.065,P value is 0.799,there was no statistically significant difference(P>0.05);the patients with different degree of carotid stenosis, detection of low cerebral blood flow perfusion of the experimental group respectively:mild 2 cases、moderate 4 cases、severe 8cases、occlusion 2 cases, Control group:mild 0 cases、moderate 4 cases、severe 9cases、occlusion 1 cases, X^2 was 0.258, P value is 0.611,there was no statistically significant difference(P>0.05).Conclusion:Application of low-dose CT perfusion imaging can evaluate cerebral blood flow perfusion hypertension and carotid stenosis TIA accuratly,Is advantageous to the client radiation dose and amount of contrast medium,At the same time reduce the incidence of contrast medium nephropathy.