不同剂量干扰素α 1b雾化治疗小儿毛细支气管炎的疗效及安全性

目的:探讨采用不同剂量干扰素α1b雾化治疗小儿毛细支气管炎的临床有效性。方法:数字随机抽取我院2015年1月至2016年1月期间接收并采用2.0μg/kg干扰素α1b雾化治疗的20例小儿毛细支气管炎患儿作为大剂量组,选取同期接收并采用1.0μg/kg干扰素α1b雾化治疗的另20例为小剂量组,选取同期接收并行常规治疗的另20例为常规组,对比分析三组治疗的疗效。结果:大剂量组临床症状改善时间、总有效率及平均住院天数均优于小剂量组、对照组,比较差异存在统计学意义,P<0.05。结论:采用2.0μg/kg干扰素α1b雾化治疗小儿毛细支气管炎的效果显著,可推广。

objective: to study the different dose of interferon alpha 1 b atomization clinical efficacy for the treatment of infantile capillary bronchitis. Methods: digital randomly from January 2015 to January 2016 receives and USES 2.0 mu g/kg interferon alpha 1 b atomization treatment of 20 cases of children with infantile capillary bronchitis as high dose group, select receive and use the same period 1.0 mu g/kg interferon alpha 1 b atomization treatment of the other 20 cases of small dose group, select the same receiving routine treatment in parallel the other 20 cases of normal group, comparison and analysis of three groups of treatment efficacy. Results: the clinical symptoms improved time, large dose group total effective rate and the average hospitalization days were better than the low-dose group and the control group, comparative differences are statistically significant, P < 0.05). Conclusion: using 2.0 mu g/kg interferon alpha 1 b atomization treatment of infantile capillary bronchitis effect is remarkable, can be promoted.