多发性一过性白点综合征眼底自发荧光特征研究

目的:观察多发性一过性白点综合征病变不同时期病变区域自发荧光表现特征。方法:回顾分析30例一过性白点综合征患者的自发荧光图像及相关检查,采用海德堡公司HRA-2共焦激光眼底血管造影仪,选取自发荧光(AF)模式,行眼底自发荧光(fundus autofluorescence,FAF)检查。结果:早期病灶区FAF表现为斑点状自发荧光增强;恢复期自发高荧光扩大融合、较前减弱;愈后病灶区FAF呈现正常自发荧光像。结论:FAF能够反映多发性一过性白点综合征病变区视网膜色素上皮层(PRE)细胞的功能和RPE细胞内脂褐质分布情况,为其诊治、预后、随访提供重要的临床价值。

Objective:To observe the fundus autofluorescence(FAF) features of multiple evanescent white dots yndrome(MEWDS). Methods:30 patients(30 eyes) diagnosed multiple evanescent white dots yndrome were reviewed. All 30 patients were examined with FAF and FAF data was analysised. Results:The images of the patients at early stage were diffuse blot and dot hyper-FAF in focal area. At recovery period the images revealed expansion and mutual fusion of hyper-FAF and less hyper-FAF than at early stage. There were showed normal spontaneous fluorescence image at later stage. Conclusion:AF can react the function and the distribution of fuscin at RPE cell. It can provide important basis for diagnosis, treatment, prognostic evaluation and following up of MEWDS.