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围手术期D二聚体联合血小板容积预测腹部手术后慢性深静脉血栓 被引量:1

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摘要 目的:探讨围手术期D二聚体(D-D)及平均血小板体积(MPV)单独或联合用于预测腹部手术后慢性深静脉血栓(DVT)发生率的诊断价值。方法:回顾性收集我院2013年1月-2015年9月普外科收治并接受腹部手术并参与最后总评估患者271例,所有患者在术后1周内均接受至少1次D-D及MPV检测,随访3月后,对慢性DVT发生率、临床特征、D-D及MPV的特异性、敏感性等指标进行综合分析。结果:慢性DVT的发生率为12.18%,单变量分析危险因素包括女性、年龄较长、合并糖尿病、较长手术时间、D-D阳性及MPV升高。MPV的敏感性、特异性均优于D-D,且与金标准超声影像学的一致性高于D-D。而当两者联合预测时,敏感性升高至0.82,但特异性降低。而阳性预测值仅0.36,但阴性预测值明显升高,此外,其与超声影像学一致性为0.64。结论:MPV、D-D、及两者的联合应用各有其特点,但三者均倾向于排除性诊断。其中,MPV的阳性预测价值最高,而两者联合应用的阴性预测值则达97%。
出处 《中国妇幼健康研究》 2016年第S2期214-215,共2页 Chinese Journal of Woman and Child Health Research
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  • 1Sakon M, Maehara Y, Yoshikawa H, et al. Incidence of venous thromboembolism following major abdominal surgery: a multi-cen- ter, prospective epidemiological study in Japan [J]. J Thromb Haemost, 2006,4(3 ):581-586.
  • 2White RH, Zhou H, Romano PS. Incidence of symptomatic venous thromboembolism after different elective or urgent surgical proce- dures[J]. Thromb Haemost, 2003,90:446-455.
  • 3Spencer FA, Lessard D, Emery C, et al. Venous thromboembolism in the outpatient setting[J]. Arch Intern Med, 2007,167:1471-1475.
  • 4Schuhe LM, O'Brien JR, Bean MC, et al. Deep vein thrombosis and pulmonary embolism after spine surgery: incidence and patient risk factors[J]. Am J Orthop (Belle Mead NJ), 2013,42(6):267-270.
  • 5Keishi Sugimachi, Hirotada Tajiri, Nao Kinjo, et al. Incidence and predictors of deep venous thrombosis after abdominal oncologic surgery: Prospective Doppler ultrasound screening [J]. J Surg Res, 2012,178(2) :657 -661.
  • 6Nick AM, Sehmeler KM, Frumovitz MM, et al. Risk of thromboem- bolic disease in patients undergoing laparoscopic gynecologic surgery[J]. Obstet Gynecol, 2010,116(4):956-961.
  • 7Buchberg B, Masoomi H, Lusby K, et al. Incidence and risk factors of venous thromboembolism in colorectal surgery:does lapamscopy impart an advantage[J]. Arch Surg, 2011,146(6):739-743.
  • 8Han JS, Park TS, Cho SY, et al. Increased mean platelet volume and mean platelet volume/platelet count ratio in Korean patients with deep vein thrombosis[J]. Platelets, 2012,7(12),[Epub ahead of print].
  • 9Brill A, Fuchs TA, Chauhan AK, et al. yon Willebrand factor-me- diated platelet adhesion is critical for deep vein thrombosis in mouse models[J]. Blood, 2011,117(4):1400-1407.
  • 10Lin YT, Tsai IC, Tsai WL,et al. Comprehensive evaluation of pa- tients suspected with deep vein thrombosis using indirect CT venography with multi-detector row technology: from protocol to interpretation[J]. Int J Cardiovasc Imaging, 2010,26 (12) :311-322.

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