摘要
目前认为慢性阻塞性肺疾病发病机制主要包括炎症反应、蛋白酶/抗蛋白酶失衡和氧化/抗氧化失衡等方面。氧化/抗氧化失衡在其中发挥着启动性的作用。抗氧化药物在COPD治疗当中已经被广泛应用,其疗效也得到了大样本临床试验的证实。研究较多的抗氧化药物主要包括硫醇化合物和Nrf2激动剂。
at present that the pathogenesis of chronic obstructive pulmonary disease mainly include inflammation, protease protease imbalances and oxidation resistance/antioxidant imbalance, etc. Oxidation/antioxidant imbalance in the start. Antioxidant drug in the treatment of COPD has been widely used, its curative effect is confirmed by a large sample of clinical trials. Study more antioxidant drugs mainly include thiol compounds and Nrf2 agonist.
出处
《中国妇幼健康研究》
2017年第S1期325-326,共2页
Chinese Journal of Woman and Child Health Research
关键词
慢性阻塞性肺疾病
氧化应激
氧化/抗氧化失衡
抗氧化药物
chronic obstructive pulmonary disease
Oxidative stress
The oxidation/antioxidant imbalance
Antioxidant drug
