5-氨基酮戊酸光动力疗法治疗宫颈尖锐湿疣的临床效果

目的:探讨5-氨基酮戊酸光动力疗法(ALA-PDT)在宫颈尖锐湿疣治疗上的临床效果及价值。方法:选取2013年10月~2016年10月我院收治的宫颈尖锐湿疣患者120例为研究对象,按照治疗方法分为A组(n=40)、B组(n=40)、C组(n=40),分别行ALA-PDT治疗、CO激光治疗及联合治疗,比较三组临床治疗效果、复发率。结果:随访6个月,A组治愈率77.5%、B组治愈率55.0%、C组治愈率87.5%,复发率A组22.5%、B组45.0%、C组12.5%,C组治疗效果显著优于A组、B组,差异显著(P<0.05),具有统计学意义。结论:在宫颈尖锐湿疣的治疗上,5-氨基酮戊酸光动力疗法(ALA-PDT)的疗效理想,复发率低,值得进一步推广应用。

Objective: To investigate the clinical effect and value of 5-aminolevulinic acid photodynamic therapy(ALA-PDT) in the treatment of cervical condyloma acuminatum. Methods: 120 cases of cervical condyloma treated by our hospital from October 2013 to October 2016 were divided into group A(n = 40), group B(n = 40), group C(group B) N = 40), respectively, ALA-PDT treatment, CO laser treatment and combination therapy, compared the three groups of clinical treatment, recurrence rate. Results: The cure rate was 77.5% in group A, 55.0% in group B, 87.5% in group C, 22.5% in group A, 45.0% in group B, 12.5% in group C, and in group C Compared with group A and B, the difference was significant(P <0.05), which was statistically significant. Conclusion: In the treatment of cervical condyloma acuminatum, the effect of 5-aminolevulinic acid(ALA-PDT) is ideal and the recurrence rate is low, which is worthy of further application.