老年晚期结直肠癌患者在替吉奥基础上联合早期姑息治疗的临床效果及对生活质量的影响

目的:探究老年晚期结直肠癌患者在替吉奥基础上联合早期姑息治的临床治疗效果。方法:选取我院2016年1月～2017年1月收治的78例老年晚期结直肠癌患者为研究对象,按照临床治疗方式不同将所有研究对象在遵循患者以及患者家属意愿的情况下随机均分为对照组和实验组,对照组38例患者给予替吉奥治疗,实验组在对照组临床治疗的基础上联合早期姑息治疗,两周后比较两组患者临床治疗效果,患者治疗前后生活质量变化。结果:实验组患者临床治疗总有效率明显高于对照组(94.8%vs81.6%),两组患者治疗后生活质量评分(QIL)均有一定程度的提高,其中实验组患者治疗后生活质量评分(QIL)增幅明显大于对照组两组患者各项数据具有明显统计学意义(P<0.05).结论:对于老年晚期结直肠癌患者在替吉奥基础上联合早期姑息治疗能有效提高患者临床治疗效果,提高患者生活质量,增进医患之间的合作关系,提高患者对临床治疗的认同感和满意率。

Objective: To explore the clinical effect of the treatment of elderly patients with advanced colorectal cancer in S-1 based on combined with early palliative treatment. Methods: in our hospital from January 2016 ～2017 year in January 78 cases of elderly patients with advanced colorectal cancer patients as the research object, according to the different ways of clinical treatment of all participants in the study were to follow the wishes of the situation as well as family members of patients were randomly divided into control group and experimental group, 38 patients in control group were treated with S-1 treatment, experimental group on the basis of the control clinical treatment combined with early palliative treatment, two weeks after the two groups of patients with clinical curative effect, changes in the quality of life of patients before and after treatment. Results: the clinical total effective rate of experimental group was significantly higher than the control group(94.8%vs81.6%), quality of life score after treatment in two groups(QIL) were improved to a certain extent, the treatment of patients in the experimental group after the quality of life score(QIL) was significantly greater than that of the control group was statistically significant in two groups of the data(P<0.05) conclusion: for elderly patients with advanced colorectal cancer in S-1 based on joint early palliative care can effectively improve the clinical treatment effect, improve the quality of life of patients, improve doctor-patient relationship, improve patient identification for clinical treatment and satisfaction rate.