两种方法在厄洛替尼致相关皮疹中的应用效果

目的:观察两种方法在非小细胞肺癌患者口服厄洛替尼致重度皮疹中的效果。方法:将2014年10月至2016年6月呼吸科收治的肺腺癌口服厄洛替尼导致重度皮疹的患者25例随机分为实验组和对照组,两组患者在给予盐酸米诺环素胶囊100mg口服2/d的同时,用1:5000呋喃西林溶液湿敷患处,实验组加用氧化锌软膏外涂,观察两组皮疹消观情况。结果:实验组总有效率100.00%,对照组总有效率为66.67%,两组总有效率比较,差异有统计学意义(P <0.05)。结论:应用1:5000呋喃西林溶液湿敷联合氧化锌软膏外涂治疗厄洛替尼致重度皮疹效果好,护理人员做好患处皮肤护理、对患者进行用药指导及心理疏导,能促进患者顺利接受治疗,增强治疗效果。

objective: to observe the effect of two methods in patients with non-small-cell lung cancer by oral erlotini. Methods: in October 2014 to June 2016 were respiratory lung adenocarcinoma of oral it for patients, leading to severe rash 25 cases were randomly divided into experimental group and control group, two groups of patients given 100 mg of minocycline hydrochloride capsule oral/2 d at the same time, with 1:50 00 nitrofurazone solution wet apply affected part, the experimental group and outside coated with zinc oxide ointment, observe two groups fades. Results: the total effective rate 100.00%, control group total effective rate was 66.67%, total effective rate comparison, similar between the two groups was statistically significant(P < 0.05). Conclusion: shi fu 1:50 00 nitrofurazone solution with zinc oxide ointment besmear outside therapy for it, cause severe rash effect is good, do, skin care and nursing for patients with medication guidance and psychological counseling, can promote patients successfully treated, enhance the efficacy of treatment.