异烟肼治疗气管、支气管结核的临床疗效与安全性观察

目的:探讨异烟肼治疗气管、支气管结核的临床疗效与安全性;方法:选取我院2013年3月-2016年10月结核门诊收治的气管、支气管结核患者60例为研究对象,观察两组患者治疗前后痰涂片结核杆菌阳性率、肺功能、临床症状改善等情况;结果:观察组患者治疗6个月后肺功能和临床症状改善情况显著优于对照组,且深部痰液涂片抗酸检查阳性率显著低于对照组;结论:异烟肼联合其他抗结核药具有显著的临床效果,能明显改善肺功能和临床症状,降低痰液涂片抗酸杆菌阳性率,值得临床推广。

objective to explore the diagnosis and treatment of isoniazid the clinical curative effect and security of the tracheal, bronchial tuberculosis;Methods:select our hospital in March 2013-in October 2016, respiratory medicine of 60 patients with tracheal and bronchial tuberculosis as the research object, observe two groups before and after treatment in patients with mycobacterium tuberculosis positive sputum smear, pulmonary function, clinical symptoms improved, and so on and so forth;Results:observation group six months after treatment in patients with pulmonary function and clinical symptoms improved significantly better than control group, and sputum smear acid to the deep positive rate was significantly lower than the control group;Conclusion:isoniazid combined other anti-tuberculosis medicine has significant clinical effect, can significantly improve pulmonary function and clinical symptoms, reducing sputum smear positive rate which acid fast bacilli, worth clinical promotion.