血浆置换治疗ANCA相关性血管炎的疗效观察与护理要点

目的:回顾分析血浆置换治疗ANCA相关性血管炎的疗效,总结护理要点。方法:选取我院肾科监护室2015年1月至2016年12月收治的ANCA相关性血管炎患者共18例,应用血浆置换联合药物治疗,观察治疗期间患者的肾功能恢复情况,结果:血浆置换结束后患者肾功能(血清肌酐水平)稳定或改善,血清ANCA转阴,髓过氧化物酶(MPO)抗体滴度下降。结论:血浆置换联合药物治疗能明显改善ANCA相关性血管炎患者的预后,患者的心理状况、血滤机及管路的维护是护理要点。

Objective: To review and analyze the efficacy of plasma exchange therapy for ANCA related vasculitis and summarize the main points of nursing. Methods: KICU in our hospital from January 2015 to December 2016 were ANCA associated vasculitis patients in 18 cases, recovery of renal function in patients during the analysis of the patient’s psychological characteristics and nursing points. Results: after the plasma exchange, the renal function(serum creatinine level) of the patients was stable or improved, and the titer of myeloperoxidase(MPO) antibody decreased. Conclusion: plasma exchange combined with drug treatment can significantly improve the prognosis of patients with ANCA related vasculitis. The observation of complications during treatment, the maintenance of blood filters and pipelines are the main points of nursing.