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右美托咪定联合小剂量舒芬太尼对臂丛麻醉的影响 被引量:2

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摘要 目的:观察右美托咪定联合小剂量舒芬太尼对臂丛神经阻滞麻醉效果的影响。方法:选择2016年1月至2017年4月就诊于我院的90例拟行上肢手术的患者为研究对象,按随机数字表法分为Ⅰ、Ⅱ、Ⅲ组各30例,臂丛阻滞效果确切后,Ⅰ组在术前15min按0.5 ug/(kg)缓慢静注右美托咪定,然后以0.4ug/(kg·h)微泵输注;Ⅱ组缓慢静注舒芬太尼0.2 ug/kg,继以微量泵输注生理盐水20 mL/h;Ⅲ组缓慢静注右美托咪定0.5ug/kg和舒芬太尼0.1ug/kg,继以微量泵输注右美托咪定0.4ug/(kg·h)。记录3组臂丛阻滞神经麻醉前(To),臂丛神经阻滞麻醉后10 min(T 1),上止血带时(T 2),手术开始后15 min(T3)、30 min(T4),手术结束时(T5)的MAP、HR、SpO2,和Ramsay镇静评分;记录术中不良反应及术后VAS。结果:Ⅰ组T2时点MAP、HR均高于Ⅱ、Ⅲ组,P均<0.05。Ⅰ、Ⅲ组时点Ramsay镇静评分均高于Ⅱ组,P均<0.05。3组的T2时点MAP均高于其他时点,Ⅰ、Ⅱ、Ⅲ组术后VAS分别为(4.3±0.5)、(1.6±0.4、(1.3±0.6)分,Ⅰ组与Ⅱ、Ⅲ组比较,P均<0.05。3组均未出现呼吸抑制、低血压、低血氧等不良反应。结论:右美托咪定联合小剂量舒芬太尼能够增强臂丛神经阻滞麻醉的镇静、镇痛效果,且安全性较好。
作者 俞灵琳
出处 《中国妇幼健康研究》 2017年第S3期456-457,共2页 Chinese Journal of Woman and Child Health Research
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