药学干预对临床合理应用喹诺酮类药物的效果分析

目的:针对使用喹诺酮类药物患者采用药学干预效果观察。方法:选取2016年4月-2017年4月在我院进行治疗的156例使用喹诺酮类药物患者及所开出的826张处方作为研究对象。按照随机数字法,分为对照组(78例,常规使用喹诺酮类药物治疗)和观察组(78例,对喹诺酮类药物使用情况进行药学干预)。比较两组患者用药后治愈率和不良反应发生率、耐药率、不合理处方发生率。结果:观察组患者喹诺酮类药物用药后治愈率达到92.30%、不良反应发生率为3.84%、耐药率为5.12%,各方面表现均显著优于对照组,差异有统计学意义(P<0.05)。对两组患者开具826张处方中,观察组不合理处方发生率为2.17%,低于对照组13.43%,差异具有统计学意义(P<0.05)。结论:针对使用喹诺酮类药物患者治疗中采用药学干预效果好,在充分发挥药效同时,有效降低了患者不良反应,值得推广。

Objective:in view of the use of quinolones were treated by medicine intervention effect observation. Selection methods: April 2016-April 2017 in ou r hospital for treatment of 156 patients with the use of quinolones and 826 prescriptions are as the research object. According to the random number method, divided into control group(78 cases, the routine use of quinolones treatment) and observation group(78 cases, the use of quinolones medicine intervention). Compare two groups of p atients after curative rate and incidence of adverse reactions, the incidence of ni, unreasonable prescription. Results: the observation group of patients after quinolones dr ugs cure rate reached 92.30%, the incidence of adverse reactions was 3.84%, the resistant rate of 3.84%, various aspects performance were significantly better than the co ntrol group, the difference was statistically significant(P < 0.05). 826 prescriptions issued on two groups of patients in observation group is unreasonable prescription rate was 2.17%, 13.43% lower than the control group, the difference statistically significant(P < 0.05). Conclusion: in view of the use of quinolones in patients with pharmac eutical intervention effect is good, at the same time give full play to the effect, effectively reduced in patients with adverse reactions, worthy of promotion.