吸氧联合压缩空气泵雾化吸入治疗AECOPD患者的效果观察

目的:观察低流量鼻导管吸氧联合压缩空气泵雾化吸入与单纯压缩空气泵雾化吸入治疗AECOPD患者的效果。方法:选取呼吸74例需行雾化吸入治疗的AECOPD患者,采用随机数字表法将患者分为观察组和对照组各37例。观察组采用压缩空气泵雾化吸入的同时连接鼻导管吸氧(2升/分),对照组采用压缩空气泵雾化吸入,观察两组患者雾化前后经皮脉氧饱和度、脉率、呼吸频率改变、咳痰效果,雾化中并发症的发生率及治疗7天后总有效率。结果:吸氧联合压缩空气雾化组患者经皮脉氧饱和度、脉率、呼吸频率改善及总有效率明显优于单纯压缩空气雾化组患者(P<0.01);两组患者临床治疗效果差异无统计学意义(P>0.05)。结论:压缩空气泵雾化吸入时联合鼻导管吸氧能有效改善AECOPD患者的缺氧症状,降低雾化治疗中并发症的发生率,值得临床应用。

Objective: To observe the effect of low-flow nasal cannula oxygen inhalation combined with compressed air pump atomization inhalation and compressed air pump atomization inhalation in patients with AECOPD. Methods: 74 AECOPD patients who needed inhalation for nebulization were enrolled. Patients were divided into observation group(37 cases) and control group(37 cases) by random number table. In the observation group, the compressed air pump was used to atomize the inhalation while the nasal cannula was connected with oxygen(2 L/min). The control group was inhaled with compressed air pump. The percutaneous oxygen saturation, pulse rate, Respiratory rate change, sputum effect, the incidence of complications in the atomization and the total effective rate after 7 days of treatment. Results: The improvement and total effective rate of percutaneous oxygen saturation, pulse rate and respiration rate were significantly better in patients with inhalation of compressed air atomization than those in the group of compressed air atomization(P <0.01). The clinical effects The difference was not statistically significant(P> 0.05). Conclusion: Compression air pump inhalation combined with nasal oxygenation can effectively improve the symptoms of hypoxia in patients with AECOPD and reduce the incidence of complications in nebulization, which deserves clinical application.