早发性皮质下血管性认知损害

Early-onset subcortical vascular cognitive impairment

血管性痴呆可能是导致早发性认知障碍最主要的原因之一,皮质下血管性认知损害(subcortical vascular cognitive impairment,SVCI)是血管性痴呆的主要亚型,而目前对于早发性SVCI的关注和研究较少。本文对早发性SVCI的流行病学、危险因素、临床及影像学特征、鉴别诊断和治疗进行综述,旨在加深临床医师对早发性SVCI的认识,提高对早发性SVCI超早期症状的识别能力。

Vascular dementia may be the one of the main causes of early-onset cognitive impairment.Subcortical vascular cognitive impairment(SVCI) is the main subgroup of vascular dementia,but there is still little attention on early-onset SVCI. This paper analyzes the epidemiology,risk factors, clinical and imaging characteristics, differential diagnosis and treatment of early-onset SVCI, aiming to improve the clinicians’ understanding of early-onset SVCI, and enhance their recognition of super-early symptoms of early-onset SVCI.