软骨肉瘤发病特征与恶性程度关系分析

The Analysis for Characteristics and Malignant Grade of Chondrosarcoma

目的分析软骨肉瘤发病特征与恶性程度关系。方法收集软骨肉瘤患者性别、年龄、发病部位等临床资料,并分析其与软骨肉瘤恶性程度级别之间的关系。结果软骨肉瘤患者中男女性别比例为1.42∶1,年龄分布曲线呈单峰波型,大部分发生于31~60岁之间,其中41~50岁年龄段发病率最高。软骨肉瘤在身体骨骼发病部位分布存在差异,好发于身体下半部骨骼,最常见发病部位是下肢骨。相对于Ⅰ级和Ⅱ级,软骨肉瘤Ⅲ级患者男性发病率明显高于女性(P<0.05),下肢骨软骨肉瘤Ⅲ级的发病率明显高于上肢骨(P<0.05),但恶性程度级别在>40岁和<40岁无明显差异(P>0.05)。结论软骨肉瘤好发于中年男性,多见于下肢骨及骨盆三角区,但其恶性程度级别与年龄无关。

Objective This study aimed to analyze the relationship between the characteristics of chondrosarcoma and the degree of malignancy.Methods The clinical data of patients with chondrosarcoma,such as gender,age and site distribution,were collected,and their relationship with the degree of malignancy of chondrosarcoma was analyzed.Results The gender ratio of male to female patients with chondrosarcoma was 1.42:1.The age distribution curve showed a single peak wave type,most of which occurred between 31 and 60 years old,and the incidence of chondrosarcoma was the highest in 41 to 50 years old.The distribution of chondrosarcoma in skeletal lesions was different.Chondrosarcoma occurred in the lower half of the body,and the most common site is lower limb bone.Compared with grade I and II,the incidence of chondrosarcoma grade III in males was significantly higher than that in females(P<0.05),and the incidence of chondrosarcoma grade III in lower limbs was significantly higher than that in upper limbs(P<0.05),but there was no significant difference in the degree of malignancy between over 40 years old and under 40 years old(P>0.05).Conclusion Chondrosarcoma is predominantly diagnosed in middle-aged males,mostly located in lower limb bones and pelvic triangle,but the grade of malignancy is not related to age.