大豆异黄酮的抗肿瘤作用研究进展

Research advance on Antitumor Effect of Soy Isoflavones

大豆异黄酮(Soybean Isoflavone,SIF)是大豆中的功能性成分而非营养成分,是一类具有雌激素样作用的生物活性物质,又称作植物雌激素(Phytoestrogen)。流行病学调查、动物体内、外实验等系统研究证实,经常食用大豆可以预防癌症、降血脂、抗动脉粥样硬化等的发生,增进人体健康,普遍认为单独服用或配合化疗应用可能是一种有效的抗癌疗法。本文拟就SIF抗肿瘤方面的研究成果作一综述。

Soybean isoflavone(SIF)is a functional component of soybeans,not a nutrient.It is a kind of bioactive substance with estrogen-like action,also known as phytoestrogen.Epidemiological investigations,animal experiments in vitro and in vivo have confirmed that regular consumption of soybeans can prevent cancer,lower blood fat,antiatherosclerosis and improve human health.It is generally believed that the use of chemotherapy alone or in combination with chemotherapy may be one of effective anti-cancer therapies.This article is intended to provide an overview of the research results of SIF anti-tumor.