自体角膜缘组织移植治疗四川高海拔藏族地区翼状胬肉

Eficacy Observation of Autologous Limbal Tissue Transplantation for Treating Pterygium in High Altitude Tibetan Areas of Sichuan Province

目的比较高海拔地区单纯翼状胬肉切除、翼状胬肉切除联合自体角膜缘组织移植术治疗翼状胬肉的临床疗效。方法 48例(54眼)翼状胬肉患者随机分为2组,A组24例(28眼)行单纯翼状胬肉切除术,B组24例(26眼)行翼状胬肉切除联合自体角膜缘组织移植术。术后随访3~9个月,比较两组术后翼状胬肉复发情况。结果 A组24例(28眼)中8眼复发,复发率28.6%;B组24例(26眼)2眼复发,复发率为7.7%。A组与B组复发率比较差异有统计学意义(=7.459,P<0.05)。结论在四川高海拔藏族地区采用翼状胬肉切除联合自体角膜缘组织移植术可有效地降低翼状胬肉术后的复发率,是目前较好的手术方式。

Objective To compare the clinical efficacy of simple pterygium excision VS pterygium excision combined with autologous corneal limbal tissue transplantation. Methods Forty-eight eyes were randomly divided into two groups: simple pterygium excision group( group A,28 eyes),pterygium excision combined with autologous corneal limbal tissue transplantation group( group B,26 eyes). All patients were followed up for 3 ~ 9 months,then the recurrence rates were compared. Results The recurrence rate was 28. 6%( 8 of 28 eyes recured) in group A,7. 7%( 2 of 26 eyes recured) in group B,there was significant difference in recurence rate between group A and group B( = 7. 459,P < 0. 05). Conclusion In the Tibetan area of Sichuan high altitude,pterygium excision combined with autologous corneal limbal tissue transplantation can effectively reduce the recurrence rate of pterygium,which is a better operation mode.