基于名医验方数据分析谈脂肪肝辨治思路与方法

Research on the Ideas and Methods of Treating Fatty Liver Disease Based on Analysis of Renowned Veteran Doctors' Experiential Effective Recipes Data

目的:通过对名老中医验方的数据分析探索脂肪肝的治疗经验。方法:收集名老中医发表的治疗脂肪肝的验方,将具体方药使用EXCEL建立数据库,运用描述性统计、相关性分析方法,对治法、药物的分布规律进行分析。结果:共纳入验方43首,其中:(1)共统计出治法表述45种,提示名老中医认为脂肪肝的病位主要在肝脾,病理因素多数痰湿瘀郁,甚则化热;(2)共使用药物115种,频次较高的主要有理气药、化痰药、活血药、清热药、祛湿药等;(3)名老中医在治疗脂肪肝时多以疏肝健脾、活血化瘀、理气化痰、清热利湿等复法组方。结论:名老中医认为脂肪肝多为复合病机,肝脾不调为本,痰湿瘀郁热为标,治法灵活,用药多属肝脾两经清化之品。

Objective: To explore the experience of treating fatty liver disease by analyzing the experiential effective recipes of renowned veteran doctors. Methods: This research collected experiential effective recipes treating fatty liver disease published by the renowned veteran doctors and established a database including all therapies and medicines,using EXCEL. Descriptive statistics and correlation analysis were used to analyze the distribution of the high frequency therapies and medicines. Results: Finally 43 recipes were collected,and we found:(1)The expressions of therapies were 45 kinds. That reminded renowned veteran doctors thought fatty liver disease's location was mainly in the liver and spleen,pathological factors were most phlegm,dampness,blood stasis,stagnation,even heat;(2)115kinds of medicines were used,the most were medicines for regulating flow of Qi,eliminating phlegm,invigorating the circulation of blood,clearing heat,dispelling dampness and so on.(3)The renowned veteran doctors were inclined to use multiple therapies,such as soothing liver and strengthening spleen,promoting blood circulation and removing blood stasis,regulating Qi-flowing for eliminating phlegm,clearing heat and damp. Conclusion: Most famous veteran doctors involved in this research agree that the pathogenesis of fatty liver disease is a kind of compound pathogenesis,which base on the disharmony of liver and spleen,and sthenia in superficiality including phlegm,dampness,blood stasis,stagnation,heat. Their therapies are flexible and medicines mostly belong to clearing liver and spleen.