通脑方治疗脑动脉硬化症的疗效以及对血脂、Hcy水平的影响

Curative Effect of Using Tongnao Recipe in the Treatment of Cerebral Arteriosclerosis and Its Influence on Blood Lipid and Hcy Level

目的:观察通脑方治疗脑动脉硬化症的疗效以及对血脂、Hcy水平的影响。方法:选择2015年1月~2016年5月来我科室治疗的脑动脉硬化患者160例,根据excel表格随机数字表法随机分为两组:西医组80例口服盐酸氟桂利嗪治疗,中药组80例给予通脑方治疗,两组均治疗3个月。比较两组患者治疗前后的血脂、Hcy水平、中医症候积分、治疗疗效以及不良反应。结果:中药组治疗后胆固醇(3.45±1.07)mmol/L、甘油三酯(1.87±0.85)mmol/L、高密度脂蛋白胆固醇水平(3.66±1.23)mmol/L显著低于西药组胆固醇(4.67±1.21)mmol/L、甘油三酯(2.36±0.73)mmol/L、高密度脂蛋白胆固醇水平(4.69±1.33)mmol/L,低密度脂蛋白胆固醇水平(1.75±1.03)mmol/L显著高于西药组(1.43±0.87)mmol/L;中药组治疗后治疗后Hcy水平(12.57±3.05)μmol/L显著低于西药组Hcy水平(13.61±3.28)μmol/L;中药组治疗有效率为91.25%显著高于西医组的77.50%;中药组不良反应发生率为1.25%显著低于西药组的8.75%。P<0.05,差异有统计学意义。结论:通脑方治疗脑动脉硬化症能降低血脂,缓解临床症状,降低Hcy水平,提高临床治愈率,安全可靠,值得推广。

Objective: To explore the effect of using Tongnao Recipe in the treatment of cerebral arteriosclerosis and its effect on blood lipid and Hcy level. Methods: Choosing from January 2015 to May 2015 to come to our department treatment of160 patients with cerebral arteriosclerosis,according to the excel spreadsheet random number table method were randomly divided into two groups: western medicine group of 80 cases of oral flunarizine hydrochloride treatment,TCM group,80 cases of cerebral side treatment,two groups were treated for 3 months. Compared the blood lipid,Hcy level,TCM syndrome score,curative effect and adverse reaction of the two groups of patients before and after treatment. Results: The Chinese traditional medicine group after treatment cholesterol was(3. 45±1. 07) mmol/L,triglycerides was(1. 87±0. 85) mmol/L,high density lipoprotein cholesterol was(3. 66±1. 23) mmol/L was significantly lower than the western medicine group cholesterol was(4. 67±1. 21) mmol/L,triglycerides was(2. 36±0. 73) mmol/L,high density lipoprotein cholesterol was(4. 69± 1. 33) mmol/L,low density lipoprotein cholesterol was(1. 75±1. 03) mmol/L,which were significantly higher than the western medicine group which was(1. 43±0. 87)mmol/L; After treatment,the Hcy level of Hcy(12. 57± 3. 05) was significantly lower than that of the western medicine groupHcy level(13. 61±3. 28) mol/L; The effective rate of TCM treatment was 91. 25%,which was significantly higher than that in the western medicine group. The adverse reaction rate of the Chinese medicine group was 1. 25%,which was significantly lower than that of the western medicine group,P< 0. 05. The difference was statistically significant. Conclusion: Treatment of cerebral arteriosclerosis can reduce blood lipid,relieve clinical symptoms,reduce Hcy level,improve clinical cure rate,safe and reliable,worth promoting.