桂枝汤加减治疗小儿厌食症临床疗效分析

Clinical Effect Analysis of Using Modified Guizhi Decoction in the Treatment of Infantile Anorexia

目的:观察桂枝汤加减治疗小儿厌食症的临床效果。方法:选取2016年2月~2018年2月我院收治的厌食症患儿110例,采用随机抽签法分为观察组与对照组各55例,对照组予以健胃消食片并补充维生素B簇等西医常规治疗,观察组予以自拟桂枝汤加减治疗,观察两组患儿治疗有效率,治疗前后患儿中医症候积分、血红蛋白(Hb)、血清Zn2+、血清Ca2+、身高及体重变化。结果:两组患儿治疗有效率分别为94.55%、81.82%,观察组治疗有效率明显高于对照组(P<0.05);两组患者治疗前中医症候积分无统计学差异(P>0.05),治疗后两组患者中医症候积分均较治疗前降低(P<0.05),且观察组中医症候积分明显低于对照组(P<0.05);治疗前两组患儿Hb、血清Zn2+、Ca2+水平均无显著差异(P>0.05),治疗后与治疗前比较均明显升高(P<0.05),且观察组Hb、血清Zn2+、Ca2+水平均显著高于对照组(P<0.05);两组患儿治疗前身高、体重均无明显差异(P>0.05),治疗后观察组身高、体重较治疗前均显著增高(P<0.05),对照组与治疗前比较无统计学差异(P>0.05),且观察组身高、体重均明显高于对照组(P<0.05)。结论:采用桂枝汤加减治疗小儿厌食症,可明显改善患儿厌食症状,增强患儿食欲及食量,纠正贫血,补充微量元素,促进机体生长发育,疗效显著,具有一定临床应用价值。

Objective:To explore the clinical effect of using Modified Guizhi Decoction in the treatment of infantile anorexia.Methods:A total of 110 children with anorexia who were admitted to the hospital during the period from February 2016 to February 2018 were randomly divided into observation group and controlled group,55 cases in each group.The controlled group was treated with western medicines such as Jianwei Xiaoshi Tablets and supplement of vitamin B.On this basis,the observation group was treated with Modified Guizhi Decoction.The treatment response rates,changes in TCM syndrome scores,hemoglobin(Hb),serum Zn2+,serum Ca2+,height and weight in both groups before and after treatment were observed.Results:The treatment response rate of the observation group was significantly higher than that of the controlled group(94.55%vs 81.82%)(P<0.05).There was no significant difference in TCM symptom scores,the level of Hb,serum Zn2+or Ca2+,height or weight between the two groups before treatment(P>0.05).TCM scores of both groups were decreased after treatment(P<0.05),and the scores of the observation group were significantly lower than those of the controlled group(P<0.05).Levels of Hb,serum Zn2+or Ca2+,height and weight of both groups were significantly increased after treatment(P<0.05),but there was no significant difference in height or weight in the control group,compared with those before treatment(P>0.05).Levels of Hb,serum Zn2+or Ca2+,height and weight in the observation group were significantly higher than those in the controlled group after treatment(P<0.05).Conclusion:The treatment with Modified Guizhi Decoction for infantile anorexia can significantly relieve anorexia symptoms,enhance the appetite and food intake of children,correct anemia,supplement trace elements,and promote the growth and development of the body,and with significant curative effect.