从五神理论辨治帕金森病非运动症状

Differentiation and Treatment of Non-motor Symptoms of Parkinson’s Disease from Five Mind Theory

帕金森病(PD)是一种常见的中老年神经系统变性疾病,中医临床诊疗多局限于脏腑辨治、八纲辨治,忽视了疾病形神并病的本质特征和该病精神心理层面的焦虑、抑郁、睡眠障碍、认知功能下降等非运动症状。五神是人类精神思维活动的本源所在,表征人类内在的本能,具有潜在性。五神理论从神、魂、魄、意、志五种基本要素的紊乱状态阐释疾病发生的根源,是中医认识躯体行为和精神心理活动的理论基础。基于五神理论辨治PD的非运动症状,要在充分理解五神理论内涵的基础上,从五神要素入手,结合其病因病机,阐明五神紊乱的致病机制,从病机层面评定疾病并确定治疗靶点,指导临床辨证用药,开辟从"五神"研究PD非运动症状的临床诊疗新方向。

Parkinson’s disease is a common senile neurodegenerative disease. TCM clinical diagnosis and treatment of Parkinson’s disease is confined to visceral syndrome differentiation and eight-principle syndrome differentiation,neglecting the essential features of complicating disease of body and mind,psychological anxiety,depression,sleep disorders,cognitive decline of non-motor symptoms in Parkinson’s disease. The five minds are the source of human mental activities,representing the inherent and potential instinct of human beings. It is the theoretical basis for the understanding of physical behaviors and mental activities of TCM,which explains the root of disease from the disorder state of the five basic elements of spirit,ethereal soul,corporeal soul,idea and will. Based on five mind theory,non-motor symptoms of Parkinson’s disease are differentiated and treated. Five mind theory and the pathogenesis of five mind disorders as the basis,the therapeutic targets should be determined from the pathogenesis levels to guide the clinical syndrome differentiation and medication and build up the new direction to study non-motor symptoms of PD from five minds.