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体外胚胎培养液代谢组学分析在评价胚胎发育潜能的研究进展 被引量:4

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摘要 代谢组学是对溶液、组织、细胞等生物样本中的小分子代谢物进行定性和定量分析,从而得到生物体受外界刺激后其代谢水平的整体变化的结果。其研究过程包括代谢组数据的采集、预处理、多变量数据分析、标记物识别和途径分析等步骤。代谢组学作为一种新兴技术,在辅助生殖技术中具有很好的应用前景。胚胎的发育和代谢是个动态过程,应用质谱分析、光谱分析和磁共振波谱技术能客观、全面、准确、无创地反映胚胎质量及其发育潜能,可作为胚胎形态学评估的补充,从而提高胚胎种植率,提高单胚胎移植的妊娠率。
出处 《山东医药》 CAS 北大核心 2015年第1期98-100,共3页 Shandong Medical Journal
基金 江苏省妇幼保健科研项目(F201347) 南通市科技计划项目(HS2013012)
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参考文献15

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