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硒与自身免疫性甲状腺炎的关系 被引量:5

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摘要 自身免疫性甲状腺炎(AITD)是以高甲状腺过氧化物酶抗体和甲状腺球蛋白抗体为特点的T细胞介导的甲状腺炎症反应。硒在体内作为谷胱甘肽过氧化物酶的活性辅助因子,可抑制甲状腺组织内的氧化反应,保护甲状腺滤泡上皮细胞免受氧化损伤,从而维护膜完整性。给予AITD患者补充硒治疗,可降低体内过氧化物酶抗体,减少自身抗体对甲状腺组织的破坏。
出处 《山东医药》 CAS 北大核心 2015年第1期104-106,共3页 Shandong Medical Journal
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