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环磷腺苷葡胺辅助治疗慢性肺源性心脏病心力衰竭疗效观察 被引量:13

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摘要 目的观察环磷腺苷葡胺辅助治疗慢性肺源性心脏病(简称肺心病)心力衰竭的疗效及安全性。方法将80例慢性肺心病心力衰竭患者随机分为观察组和对照组,各40例,两组给予抗感染、利尿、纠正电解质及酸碱平衡紊乱、低流量吸氧等常规治疗,观察组静滴环磷腺苷葡胺,连续治疗7 d,观察治疗前后咳嗽、咳痰、活动耐力、肺部体征及动脉血气检查结果。结果观察组总有效率92.50%,对照组70.00%,P<0.05;与治疗前比较,两组治疗后Pa O2、Sa O2明显增加、Pa CO2明显降低(P均<0.05)。与对照组比较,观察组治疗后Pa O2、Sa O2、Pa CO2变化更显著(P均<0.05)。观察组药物不良反应发生率5.00%,对照组2.50%,P>0.05。结论环磷腺苷葡胺治疗慢性肺心病心力衰竭安全、有效。
出处 《山东医药》 CAS 北大核心 2015年第4期39-40,共2页 Shandong Medical Journal
基金 上海市崇明县科学技术发展资金项目(CKY2012-27)
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