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免疫细胞治疗联合化疗对晚期卵巢癌患者疗效及血清CCL-18水平的影响 被引量:4

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摘要 目的观察免疫细胞治疗联合化疗治疗晚期卵巢癌的效果,以及对患者血清CCL-18水平的影响。方法将66例Ⅳ期卵巢癌患者机分为观察组29例和对照组37例,对照组单纯采用化疗,观察组在化疗基础上联合免疫细胞治疗。观察治疗效果,采用ELISA法检测两组治疗前后血清CCL-18,记录生存情况。结果观察组总有效率为65.52%,对照组40.54%,P<0.05;与治疗前比较,两组治疗后血清CCL-18均降低,且观察组下降更明显(P均<0.05);观察组中位无病生存期为7.96个月、中位总生存期为10.84个月,对照组分别为6.23、9.33个月,P均<0.05。结论免疫细胞治疗联合化疗能提高晚期卵巢癌患者的疗效,降低血清CCL-18水平,延长生存期。
作者 黄少江
出处 《山东医药》 CAS 北大核心 2015年第8期66-67,共2页 Shandong Medical Journal
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  • 1Brian K. Zebrowski MD,Wenbiao Liu MD,Karen Ramirez BS,Yoshito Akagi MD,Gordon B. Mills MD,Lee M. Ellis MD.Markedly Elevated Levels of Vascular Endothelial Growth Factor in Malignant Ascites[J]. Annals of Surgical Oncology . 1999 (4)
  • 2Girieca Lorusso,Curzio Rüegg.The tumor microenvironment and its contribution to tumor evolution toward metastasis[J]. Histochemistry and Cell Biology . 2008 (6)
  • 3Kazutoshi Takahashi,Shinya Yamanaka.Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors[J]. Cell . 2006 (4)
  • 4Guoqiang Hua,Tin Htwe Thin,Regina Feldman,Adriana Haimovitz–Friedman,Hans Clevers,Zvi Fuks,Richard Kolesnick.Crypt Base Columnar Stem Cells in Small Intestines of Mice Are Radioresistant[J]. Gastroenterology . 2012 (5)
  • 5Maria Lee,Eun Ji Nam,Sang Wun Kim,Sunghoon Kim,Jae Hoon Kim,Young Tae Kim.Prognostic Impact of the Cancer Stem Cell–Related Marker NANOG in Ovarian Serous Carcinoma[J]. International Journal of Gynecological Cancer . 2012 (9)
  • 6Kristel Kemper,Pramudita R. Prasetyanti,Wim De Lau,Hans Rodermond,Hans Clevers,Jan Paul Medema.Monoclonal Antibodies Against Lgr5 Identify Human Colorectal Cancer Stem Cells[J]. STEM CELLS . 2012 (11)
  • 7Nina Karthaus,Ruurd Torensma,Jurjen Tel.Deciphering the Message Broadcast by Tumor-Infiltrating Dendritic Cells[J]. The American Journal of Pathology . 2012 (3)
  • 8Jane E. Visvader,Geoffrey J. Lindeman.Cancer Stem Cells: Current Status and Evolving Complexities[J]. Cell Stem Cell . 2012 (6)
  • 9Jeffrey A. Magee,Elena Piskounova,Sean J. Morrison.Cancer Stem Cells: Impact, Heterogeneity, and Uncertainty[J]. Cancer Cell . 2012 (3)
  • 10Eiman Hasby.Weapons Ovarian Epithelial Tumors May Use in Immune Escape: An Immunohistochemical Correlational Study[J]. Pathology & Oncology Research . 2012 (2)

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