摘要
目的评价糖尿病患者甲状腺癌的发病风险。方法采用Meta分析对1990~2014年MEDLINE、PUBMED、EMBASE、WOS等数据库收录的相关文献进行统计分析。结果共筛选出13篇相关文献。Meta分析显示,同非糖尿病患者相比,糖尿病患者甲状腺癌的发病风险高[RR=1.180,95%CI=(1.080,1.280),P=0.000];男性糖尿病患者甲状腺癌发病风险差异无统计学意义[RR=1.110,95%CI=(0.800,1.530),P=0.546];女性糖尿病患者甲状腺癌发病风险高[RR=1.400,95%CI=(1.17,1.68),P=0.000]。结论糖尿病患者甲状腺癌的发病风险相对无糖尿病患者高,且女性糖尿病患者更易发病。
Objective To evaluate the relative risk of thyroid cancer in patients with diabetes mellitus( DM). Methods Using Meta-analysis to analyze the related articles( 1990-2014) searched from MEDLINE,PUBMED,EMBASE and WOS. Results A total of 13 articles were screened out,and the number of cases was 4276. The meta-analysis showed that: the relative risk( RR) of thyroid cancer in DM patients was higher than that of patients without DM [RR = 1. 180,95% CI =( 1. 080,1. 280),P = 0. 000]. No statistical difference was found in the RR of thyroid cancer of male DM patients [RR = 1. 110,95% CI =( 0. 800,1. 530),P = 0. 546 ],and the risk of thyroid cancer in female DM patients was higher [RR = 1. 400,95% CI =( 1. 17,1. 68),P = 0. 000]. Conclusion The RR of thyroid cancer in DM patients was high than that of patients without DM,and the risk of female DM patients was higher.
出处
《山东医药》
CAS
北大核心
2015年第9期12-14,共3页
Shandong Medical Journal
基金
国家自然科学基金资助项目(6137106)
