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冠心病伴牙周炎患者牙周基础治疗前后血清、龈沟液中PAF水平变化 被引量:3

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摘要 目的观察冠心病伴牙周炎患者牙周基础治疗前后血清、龈沟液中血小板活化因子(PAF)水平变化。方法选取冠心病伴中、重度慢性牙周炎患者38例(A组),中、重度慢性牙周炎患者41例(B组),两组均实施牙周基础治疗,共治疗4次,前3次为每周1次,第3次治疗2周后复诊行第4次治疗,治疗时间共2个月;另选30例健康体检者作对照(C组)。所有受试对象均进行牙周专科检查,并于初诊时及第4次治疗结束2周后采集血清及龈沟液,采用酶联免疫吸附法检测血清及龈沟液PAF。结果 A组治疗前血清、龈沟液PAF水平分别为(196.38±23.45)、(327.18±45.16)pg/m L,B组治疗前血清、龈沟液PAF水平分别为(187.95±38.45)、(368.24±46.78)pg/m L,C组血清、龈沟液PAF水平分别为(65.38±23.68)、(13.71±1.87)pg/m L,A、B组治疗前分别与C组比较,P均<0.05。A组治疗前后血清PAF水平分别为(196.38±23.45)、(137.46±36.78)pg/m L,龈沟液PAF水平分别为(327.18±45.16)、(130.24±35.17)pg/m L,治疗前后比较,P均<0.05;B组治疗前后血清PAF水平分别为(187.95±38.45)、(109.73±56.87)pg/m L,龈沟液PAF水平分别为(368.24±46.78)、(236.73±32.23)pg/m L,治疗前后比较,P均<0.05。结论牙周基础治疗可降低冠心病伴牙周炎患者血清及龈沟液中PAF水平。
出处 《山东医药》 CAS 北大核心 2015年第11期73-75,共3页 Shandong Medical Journal
基金 辽宁省医学高峰建设工程重点科研项目(200909)
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参考文献7

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