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血液miRNA检测在结直肠癌诊断、预后及化疗疗效评估中的应用进展 被引量:6

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摘要 微小RNA(miRNA)可作为癌基因与抑癌基因在多种恶性肿瘤组织中异常表达,且在肿瘤的发生、发展中发挥着重要的生物学作用。近年研究发现,miRNA不仅存在于肿瘤组织中,还稳定的存在于血液中。血液中的miRNA可作为潜在的生物标志物应用于结直肠癌(CRC)的早期诊断、预后判断以及化疗监测。本文总结了血液中miRNA检测在CRC早期诊断、预后监测、化疗疗效评估中的应用情况,为此病的早期诊断、预后判断及化疗敏感性监测提供了一个全新的视角。
作者 冯君兰 汪昱
出处 《山东医药》 CAS 北大核心 2015年第11期98-100,共3页 Shandong Medical Journal
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参考文献16

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