期刊文献+

84例上皮性卵巢癌合并血小板增多症患者实验室检查结果分析 被引量:2

下载PDF
导出
摘要 目的分析上皮性卵巢癌(EOC)合并血小板增多症患者的实验室检查特征。方法回顾性分析84例EOC患者(观察组)和55例卵巢良性肿瘤患者(对照组)的实验室检查结果。结果观察组术前血小板计数明显、血小板增多症发生率均高于对照组,且EOC晚期患者高于早期,P均<0.05。EOC合并血小板增多症患者术前血清CA125、人附睾上皮分泌蛋白4(HE4)、纤维蛋白原(FIB)、D-二聚体(D-D)水平和阳性率,以及中晚期、腹水、淋巴结转移所占比率均高于血小板正常者(P均<0.01),并且其血小板计数与术前血CA125、HE4、FIB、D-D水平无明显相关性(P均>0.05)。结论 EOC合并血小板增多症患者病情更严重,各检查指标的阳性率更高。
出处 《山东医药》 CAS 北大核心 2015年第28期61-62,共2页 Shandong Medical Journal
  • 相关文献

参考文献14

  • 1Joshua G. Cohen,Arthur-Quan Tran,B.J. Rimel,Ilana Cass,Christine S. Walsh,Beth Y. Karlan,Andrew J. Li.Thrombocytosis at secondary cytoreduction for recurrent ovarian cancer predicts suboptimal resection and poor survival[J]. Gynecologic Oncology . 2014 (3)
  • 2S.K. Allensworth,C.L. Langstraat,J.R. Martin,M.A. Lemens,M.E. McGree,A.L. Weaver,S.C. Dowdy,K.C. Podratz,J.N. Bakkum-Gamez.Evaluating the prognostic significance of preoperative thrombocytosis in epithelial ovarian cancer[J]. Gynecologic Oncology . 2013
  • 3Myriam Labelle,Shahinoor Begum,Richard O. Hynes.Direct Signaling between Platelets and Cancer Cells Induces an Epithelial-Mesenchymal-Like Transition and Promotes Metastasis[J]. Cancer Cell . 2011 (5)
  • 4N. M.BAMBACE,C. E.HOLMES.The platelet contribution to cancer progression[J]. Journal of Thrombosis and Haemostasis . 2011 (2)
  • 5Shashank Jain,John Harris,Jerry Ware.Platelets: Linking Hemostasis and Cancer[J]. Arteriosclerosis, Thrombosis, and Vascular Biology . 2010 (12)
  • 6Peter M Rothwell,Michelle Wilson,Carl-Eric Elwin,Bo Norrving,Ale Algra,Charles P Warlow,Tom W Meade.Long-term effect of aspirin on colorectal cancer incidence and mortality: 20-year follow-up of five randomised trials[J]. The Lancet . 2010 (9754)
  • 7C. E. Holmes,J. E. Levis,D. L. Ornstein.Activated platelets enhance ovarian cancer cell invasion in a cellular model of metastasis[J]. Clinical & Experimental Metastasis . 2009 (7)
  • 8Andrew J Li,Alison C Madden,Ilana Cass,Ronald S Leuchter,Leo D Lagasse,Beth Y Karlan.The prognostic significance of thrombocytosis in epithelial ovarian carcinoma[J]. Gynecologic Oncology . 2003 (1)
  • 9Stone Rebecca L,Nick Alpa M,McNeish Iain A,Balkwill Frances,Han Hee Dong,Bottsford-Miller Justin,Rupaimoole Rajesha,Armaiz-Pena Guillermo N,Pecot Chad V,Coward Jermaine,Deavers Michael T,Vasquez Hernan G,Urbauer Diana,Landen Charles N,Hu Wei.Paraneoplastic thrombocytosis in ovarian cancer. The New England Quarterly . 2012
  • 10Zeimet A G,Marth C,Müller-Holzner E,Daxenbichler G,Dapunt O.Significance of thrombocytosis in patients with epithelial ovarian cancer. American journal of obstetrics and gynecology . 1994

共引文献1

同被引文献31

引证文献2

二级引证文献6

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部