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PCV-VG单肺通气模式对老年食管癌根治术患者气管灌洗液中炎性因子水平的影响 被引量:6

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摘要 目的探讨压力控制容量保证(PCV-VG)单肺通气模式对老年食管癌根治术患者气管灌洗液中炎性因子水平的影响。方法将择期行食管癌根治术、年龄>60岁的老年患者40例随机分为观察组和对照组各20例,两组全麻后分别行PCV-VG、单肺通气多容量控制通气(VCV)模式下单肺通气。两组分别于单肺通气开始时(T0)以及单肺通气开始后1(T1)、2(T2)、3(T3)h收集气管灌洗液,采用ELISA法检测TNF-α、IL-6和IL-8水平。结果两组术中气管灌洗液TNF-α、IL-6、IL-8水平均呈进行性升高,T1、T2、T3时点的气管灌洗液TNF-α、IL-6、IL-8水平均高于同组T0时点,且对照组均高于观察组,P均<0.05。结论与VCV模式下单肺通气比较,PCV-VG模式对老年食管癌根治术患者气管灌洗液中TNF-α、IL-6和IL-8水平的影响较小。
出处 《山东医药》 CAS 北大核心 2015年第32期57-58,共2页 Shandong Medical Journal
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  • 1T. K. Kondratieva,I. A. Linge,E. V. Kondratieva,A. V. Dyatlov,M. S. Drutskaya,R. V. Zvartsev,S. A. Nedospasov,A. S. Apt.Formation of compact aggregates of B-lymphocytes in lung tissue during mycobacterial infection in mice depends on TNF production by these cells and is not an element of the host’s immunological protection[J]. Biochemistry (Moscow) . 2014 (12)
  • 2Caron M. Hong,Da-Zhong Xu,Qi Lu,Yunhui Cheng,Vadim Pisarenko,Danielle Doucet,Margaret Brown,Seena Aisner,Chunxiang Zhang,Edwin A. Deitch,Ellise Delphin.Low Tidal Volume and High Positive End-Expiratory Pressure Mechanical Ventilation Results in Increased Inflammation and Ventilator-Associated Lung Injury in Normal Lungs[J]. Anesthesia & Analgesia . 2010 (6)
  • 3S.‐C.KO,H.ZHANG,J. J.HAITSMA,K.‐C.CHENG,C.‐F.LI,A. S.SLUTSKY.Effects of PEEP levels following repeated recruitment maneuvers on ventilator‐induced lung injury[J]. Acta Anaesthesiologica Scandinavica . 2008 (4)
  • 4Bhattacharya S,Sen N,Yiming MT,et al.High tidal volume ventilation induces proinflammatory signaling in rat lung endothelium. American Journal of Respiratory Cell and Molecular Biology . 2003
  • 5De Prost N,Dreyfuss D.How to prevent ventilator-induced lung injury[J]?. Minerva Anestesiologica . 2012
  • 6Checkley William,Brower Roy,Korpak Anna,Thompson B Taylor.Effects of a clinical trial on mechanical ventilation practices in patients with acute lung injury. American Journal of Respiratory and Critical Care Medicine . 2008
  • 7Holt SJ,Sanders RC,Thurman TL,et al.An evaluation of Automode, a computer-controlled ventilator mode, with the Siemens Servo 300A ventilator, using a porcine model. Respiratory Care . 2001
  • 8Blidner AG,Salatino M,Mascanfroni ID,et al.Differential response of myeloid-derived suppressor cells to the nonsteroidal antiinflammatory agent indomethacin in tumor-associated and tumorfree microenvironments. J Immunol . 2015

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