电视胸腔镜辅助微创切口肺癌根治术治疗非小细胞肺癌的临床效果

Clinical research about video-assisted mini-thoracotomy in treatment of non-small-cell lung cancer

目的探讨电视胸腔镜辅助微创切口肺癌根治术治疗非小细胞肺癌的临床效果及预后。方法回顾性分析95例电视胸腔镜辅助微创切口肺癌根治术(微创组)与94例传统开胸肺癌根治术(常规组)患者的临床资料,对比两组疗效及预后。结果微创组术中出血量、引流管留置时间、镇痛药使用次数、术后并发症及术后住院时间均少于常规组(P均<0.05);两组手术时间、淋巴结清除数差异无统计学意义(P均>0.05);两组术后无疾病进展生存期和总生存期差异无统计学意义(P均>0.05)。结论电视胸腔镜辅助微创切口肺癌根治术治疗非小细胞肺癌可完成肿瘤的彻底切除和系统淋巴结清扫,在远期疗效上亦不逊于常规开胸手术,且创伤小、恢复快。

Objective To investigate the clinical efficacy of video-assisted mini-thoracotomy( VAMT) in the treatment of non-small-cell lung cancer( NSCLC) and the prognosis. Methods Ninety-five patients treated with VAMT( minimally invasive group) and 94 patients treated with conventional thoracotomy( conventional group) received the radical resection of pulmonary carcinoma. The clinical data of the two groups were retrospectively analyzed and we compared the curative effect and the prognosis of the two groups. Results The blood loss,drainage tube indwelling time,the frequency of using analgesics,postoperative complications and postoperative hospital stay in patients of the minimally invasive group were less than those of the conventional group,and significant difference was found between the two groups( all P < 0. 05).No statistically significant differences were found in the operative time and the number of lymph nodes removed between the two groups( all P > 0. 05). There were no significant differences in the overall survival after surgery and progression-free survival between the two groups( all P > 0. 05). Conclusions VAMT in the treatment of NSCLC can complete the radical resection of the tumor and the lymph node system. The long-term effect of VAMT is not inferior to the conventional thoracotomy,including less trauma and faster recovery.