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艾司洛尔对感染性休克患者血流动力学及预后的影响 被引量:6

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摘要 目的探讨超短效β受体阻滞剂艾司洛尔对感染性休克患者血流动力学及预后的影响。方法选择感染性休克患者100例,随机分为观察组和对照组各50例,两组均给予早期目标导向治疗,另外观察组持续静脉泵入艾司洛尔72 h。两组分别于治疗前后检测血流动力学指标,记录去甲肾上腺素(NA)维持量,测定动脉血乳酸(Lac)、中心静脉血氧饱和度及血糖(Glu)水平,心脏超声检测心功能指标,记录住院期间并发症发生率及病死率。结果与治疗前比较,观察组治疗24、48、72 h心率减慢、每搏指数升高,NA维持量、Lac水平、Glu水平、E/A值下降(P均<0.05),与对照组治疗后同期比较差异有统计学意义(P均<0.05)。观察组住院期间急性肾损伤、ARDS的发生率及病死率均低于对照组(P均<0.05)。结论艾司洛尔可降低感染性休克患者心率、增加每搏输出量、改善组织灌注状况,降低ARDS的发生率及病死率。
出处 《山东医药》 CAS 北大核心 2015年第41期70-72,共3页 Shandong Medical Journal
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