期刊文献+

溃疡性结肠炎患者血清溶血磷脂酸、肿瘤坏死因子α水平变化及意义 被引量:1

下载PDF
导出
摘要 目的检测溃疡性结肠炎(UC)患者血清溶血磷脂酸(LPA)及肿瘤坏死因子(TNF-α)水平,探讨其意义。方法选取UC患者30例(UC组),健康体检者30例(对照组)。采用ELISA法检测两组血清LPA、TNF-α,分析UC患者血清LPA与TNF-α水平的相关性。结果 UC组及对照组血清LPA水平分别为(3.75±0.58)、(1.34±0.18)μmol/L,P<0.05;TNF-α水平分别为(64.00±0.43)、(20.16±2.60)ng/L,P<0.05。随着UC患者病情的加重,血清LPA、TNF-α水平逐渐升高(P均<0.05)。UC患者血清LPA与TNF-α呈正相关(r=0.878,P<0.05)。结论 UC患者血清LPA、TNF-α水平升高,检测两者水平有助于判断UC病情。
出处 《山东医药》 CAS 北大核心 2015年第44期50-51,共2页 Shandong Medical Journal
  • 相关文献

参考文献7

  • 1Ashok Kumar Pandurangan,Salmiah Ismail,Zeinab Saadatdoust,Norhaizan Mohd. Esa,Ryuichi Morishita.Allicin Alleviates Dextran Sodium Sulfate- (DSS-) Induced Ulcerative Colitis in BALB/c Mice[J]. Oxidative Medicine and Cellular Longevity . 2015
  • 2Joseph D. Feuerstein,Adam S. Cheifetz.Ulcerative Colitis[J]. Mayo Clinic Proceedings . 2014 (11)
  • 3Lani Prideaux,Michael A Kamm,Peter P De Cruz,Francis K L Chan,Siew C Ng.Inflammatory bowel disease in Asia: A systematic review[J].Journal of Gastroenterology and Hepatology.2012(8)
  • 4Ji Woong Choi,Deron R. Herr,Kyoko Noguchi,Yun C. Yung,Chang-Wook Lee,Tetsuji Mutoh,Mu-En Lin,Siew T. Teo,Kristine E. Park,Alycia N. Mosley,Jerold Chun.LPA Receptors: Subtypes and Biological Actions[J]. Annual Review of Pharmacology and Toxicology . 2010
  • 5Partyka Robert,Gonciarz Maciej,Ja?owiecki Przemys?aw,Kokocińska Danuta,Byrczek Tomasz.VEGF and metalloproteinase 2 (MMP 2) expression in gastric cancer tissue. Medical science monitor : international medical journal of experimental and clinical research . 2012
  • 6Reeves H L,Thompson M G,Dack C L,et al.The role of phosphatidic acid in platelet-derived growth factor-induced proliferation of rat hepatic stellate cells. Hepatology . 2000
  • 7Singh D,Srivastava S,Pradhan M,et al.Inflammatory bowel disease:pathogenesis,causative factors,issues,drug treatment strategies,and delivery approaches. Critical Reviews in Therapeutic Drug Carrier Systems . 2015

共引文献5

同被引文献6

引证文献1

二级引证文献33

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部