1%利多卡因复合0.25%丁卡因液与2%利多卡因应用于上腹部手术时硬膜外麻醉的比较

Comparison of Efficiency Between Compound Injection of 0.25% Tetracaine and 1% Lidocaine and Single Use of 2% Lidocaine in Upper Abdomenal Operation by Epidural Block

目的 :比较 1%利多卡因复合 0 2 5 %丁卡因液与 2 %利多卡因硬膜外腔麻醉的效果和不良反应。方法 :采用随机双盲研究 1%利多卡因复合 0 2 5 %丁卡因液进行硬膜外腔注射 (实验组 ) 30例 ,2 %利多卡因 (对照组 )30例 ,观察指标分为硬膜外腔阻滞麻醉时效评定 ;阻滞最高节段数 ;阻滞最低节段数 ;VAS疼痛评分 ;肌松质量和镇痛效果的评定。术中不良反应以及生命体征的改变。结果 :1%利多卡因复合 0 2 5 %丁卡因液在麻醉时效、麻醉效能和麻醉效果上比 2 %利多卡因硬膜外腔麻醉 ,作用时间延长 ,麻醉平面扩大 ,有统计学意义。而不良反应两组间无统计学意义。结论 :1%利多卡因复合 0 2 5 %丁卡因液在麻醉时效、麻醉效能和麻醉效果上优于 2 %利多卡因硬膜外腔麻醉。

Objective:To compare the efficiency and side-reaction between the compound injection of 0 25% tetracaine and 1% lidocaine and single use of 2% lidocaine in upper abdominal operation by epidural block.Methods:Sixty patients being conducted with epidural block during upper abdominal operation were divided into 2 groups by random.Compound injection of 1% tetracaine and 0 5% lidocaine were used in case group,and 2% lidocaine were used in control group.The pain was used the VAS elimination,and the side-reaction after injection were observed as well.Results:The anesthesia efficiency was significantly better in case group than in the control group.And no significant difference was observed in the side-reaction in the 2 groups.Conclusions:Comparing with single use of 2% Lidocaine,the compound injection of 0 25% tetracaine and 1% lidocaine through epidural block could improve the anesthesia efficiency in the operations of upper abdomem.