半乳糖凝集素-3与肾脏疾病的关系

Relationship between galectin-3 and kidney disease

目前已有许多研究显示半乳糖凝集素家族中的半乳糖凝集素-3参与多种疾病病理生理过程,其在肾脏病中承担角色的研究已有诸多进展,值得学界关注。本篇将对半乳糖凝集素-3在肾脏表达、慢性肾脏病、急性肾损伤和肾移植中的潜在作用进行综述。

Many studies have shown that galectin-3,a member of the galectins family,was involved in the pathophysiological processes of various diseases.Researches on the role of galectin-3 in kidney diseases have progressed,and are worthy of academic concern.This article reviewed the kidney expression of galectin-3 as well as the potential role of it in chronic kidney disease,acute kidney injury,and kidney transplantation.