氧化石墨烯与核酸适配体在检测方面应用的进展

Application progress of graphene oxide and aptamer in detection

核酸适配体是一类能与靶物质高亲和力和特异性结合的寡核苷酸链,氧化石墨烯是一种具有多种独特理化性质的新兴材料,近年来它逐渐应用到了核酸适配体领域并取得了一系列进展。本文综述了近年来氧化石墨烯与核酸适配体针对小分子及金属离子、生物大分子和细胞等不同靶物质的检测方面的应用进展,以期为氧化石墨烯在适配体检测领域的大规模应用提供参考。

Aptamers are oligonucleotides which can combine targets with high affinity and specificity.Graphene oxide is a kind of new material with many unique physical and chemical properties.Recently, graphene oxide is gradually applied to the field of aptamers and has made a series of progress.This review focused on the application progress of graphene oxide and aptamers in the detection of different targets including small molecules and metal ion, biomacromolecules and cells in order to provide references for the mass application of graphene oxide and aptamers in the field of detection .