姜多靶点多途径抗癌机制研究进展

Research progress on anticancer mechanism of ginger via multi-targets and multi-pathways

综述姜多靶点多途径抗癌机制研究进展。姜含有姜辣素、挥发油等多种植物活性成分,具有抗炎、抗氧化、抑制多种癌细胞增殖、促进癌细胞凋亡、调节免疫、抗病原微生物、抑制癌细胞浸润转移、减缓癌症化疗药毒副作用等多种药理作用。姜及其提取物对癌症的防治具有多成分、多靶点、多途径、多环节、安全无毒的特点,在肺癌、前列腺癌、直肠癌、皮肤癌、肝癌、乳腺癌等的防治中显示出明显效果。

This paper reviews the research progress on anticancer mechanism of ginger via multi-targets and multi-pathways. Ginger contains many kinds of plant active ingredients such as gingerol,volatile oil and so on,and shows many pharmacological effects such as anti-inflammatory,antioxidation,inhibiting the proliferation of various cancer cells,promoting the apoptosis of cancer cells,regulating immune,anti-pathogenic microorganism,inhibiting the invasion and metastasis of cancer cells,and slowing down the toxic and side effects of cancer chemotherapy drugs. Ginger and its extracts show many characteristics in the prevention and treatment of cancer,including multiple components,multiple targets,multiple pathways,multiple links,safe and nontoxicity,and present obvious effects in the prevention and treatment of lung cancer,prostate cancer,rectal cancer,skin cancer,liver cancer,breast cancer and so on.