摘要
Objective: To evaluate complications that occurred during the post-partum period for patients with preeclampsia or HELLP syndrome. Study design: Retrospective analysis of 453 patients. The main outcome measures were maternal complications during post-partum period: fever >38.5° C with proved infection, abdominal or perineal abscess, thrombo-embolic events, reoperation, need for blood transfusion, acute renal failure, eclampsia or disseminated intravascular coagulation. Statistic tests included univariate and multivariate analysis with stepwise descending logistic regression. Results: Patients were divided into 305 preeclampsia (67.3% ) and 20 HELLP syndrome (4.4% ), 128 (28.3% ) had both. Eighty-five patients (18.8% ) had at least one post-partum complication. The most frequent complication was infection: fever (41 patients, 9.1% ) and abscess (30 patients, 6.6% ). Twenty-six transfusions (5.7% ), 10 disseminated intravascular coagulation (2.2% ), seven thrombo-embolic events (1.5% ), seven reoperations (1.5% ) and one eclampsia (0.2% ) were observed. There was no acute renal failure, no pulmonary oedema and no maternal death. Stepwise logistic regression showed five independent risk factors associated with post-partum complications: ascites or pulmonary oedema (OR: 1.84, 95% CI: 1.01- 3.37), platelet count < 100 000/mm3 (OR: 1.96, 95% CI: 1.18- 3.26), serum acid uric > 360 μ mol/l (OR: 2.36, 95% CI: 1.22- 4.52), serum creatinine > 120 μ mol/l (OR: 2.99, 95% CI: 1.32- 6.78), and proteinuria > 5 g/l (OR: 1.80, 95% CI: 1.06- 3.05). Conclusion: We conclude that severity criteria for preeclampsia or HELLP syndrome combined with caesarean section increased the risk of complication during the post-partum period.
Objective: To evaluate complications that occurred during the post-partum period for patients with preeclampsia or HELLP syndrome. Study design: Retrospective analysis of 453 patients. The main outcome measures were maternal complications during post-partum period: fever >38.5° C with proved infection, abdominal or perineal abscess, thrombo-embolic events, reoperation, need for blood transfusion, acute renal failure, eclampsia or disseminated intravascular coagulation. Statistic tests included univariate and multivariate analysis with stepwise descending logistic regression. Results: Patients were divided into 305 preeclampsia (67.3% ) and 20 HELLP syndrome (4.4% ), 128 (28.3% ) had both. Eighty-five patients (18.8% ) had at least one post-partum complication. The most frequent complication was infection: fever (41 patients, 9.1% ) and abscess (30 patients, 6.6% ). Twenty-six transfusions (5.7% ), 10 disseminated intravascular coagulation (2.2% ), seven thrombo-embolic events (1.5% ), seven reoperations (1.5% ) and one eclampsia (0.2% ) were observed. There was no acute renal failure, no pulmonary oedema and no maternal death. Stepwise logistic regression showed five independent risk factors associated with post-partum complications: ascites or pulmonary oedema (OR: 1.84, 95% CI: 1.01- 3.37), platelet count < 100 000/mm3 (OR: 1.96, 95% CI: 1.18- 3.26), serum acid uric > 360 μ mol/l (OR: 2.36, 95% CI: 1.22- 4.52), serum creatinine > 120 μ mol/l (OR: 2.99, 95% CI: 1.32- 6.78), and proteinuria > 5 g/l (OR: 1.80, 95% CI: 1.06- 3.05). Conclusion: We conclude that severity criteria for preeclampsia or HELLP syndrome combined with caesarean section increased the risk of complication during the post-partum period.
