摘要
Objective: To assess the effect of parity on endovascular trophoblastic invasion in early pregnancy. Design: Observational study. Setting: Teaching hospital. Patient(s): Healthy women at 10-14 weeks of gestation. Intervention(s): Surgical termination of pregnancy for nonmedical reasons. Main Outcome Measure(s): Products of conception were blindly examined histologically with regard to the extent of decidual endovascular trophoblast invasion. Result(s): Samples were obtained from 20 nulliparous and 10 parous women. The presence of normal intradecidual endovascular trophoblast invasion was identified with a similar frequency in both groups (P=.28). However, the proportion of decidual vessels with endovascular trophoblast invasion was significantly higher in parous women (60% ) compared with nulliparous women (32% , P < .001). Conclusion(s): Endovascular trophoblast invasion in early pregnancy is more extensive in parous women who already had an uncomplicated pregnancy than in nulliparous women.
Objective: To assess the effect of parity on endovascular trophoblastic invasion in early pregnancy. Design: Observational study. Setting: Teaching hospital. Patient(s): Healthy women at 10-14 weeks of gestation. Intervention(s): Surgical termination of pregnancy for nonmedical reasons. Main Outcome Measure(s): Products of conception were blindly examined histologically with regard to the extent of decidual endovascular trophoblast invasion. Result(s): Samples were obtained from 20 nulliparous and 10 parous women. The presence of normal intradecidual endovascular trophoblast invasion was identified with a similar frequency in both groups (P=.28). However, the proportion of decidual vessels with endovascular trophoblast invasion was significantly higher in parous women (60% ) compared with nulliparous women (32% , P < .001). Conclusion(s): Endovascular trophoblast invasion in early pregnancy is more extensive in parous women who already had an uncomplicated pregnancy than in nulliparous women.
