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中药大黄中蒽醌衍生物成分分析及其稳定性 被引量:11

The Analysis of Anthraquinone Derivate Component and Its Stability in Rhubarb
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摘要 体外抗菌实验证明,中药大黄对一些真菌、细菌均有较好的抑制效果,其抗菌活性成分主要为游离蒽醌衍生物中的游离大黄酸类等物质.以1,8 二羟基蒽醌为标准物,采用比色法对这类物质进行了定量分析,并对其在不同温度、pH值、光照等条件下的稳定性进行了研究,结果表明,活性成分具有很好的热稳定性,pH值稳定性为酸性>中性>碱性,在相同pH值条件下室内自然光照的稳定性优于日光照射. The experimental result in vitro showed that Chinese herbal medicine rhubarb has inhibitory effect on fungi and bacteria. The main components of active antibiotic substances of rhubarb were free anthraquinone derivate and free rhein substance. The colorimetry was used to measure the content with 1,8dioxyanthraquinone used as the standard substance. The stability of anthraquinone derivate was studied under the different conditions, such as temperature, pH, light. The result showed that the active substances had a good stability to heat. In different pH conditions, the highest stability was found in the acid environment, followed by the neutral and then the alkali environment. The stability under room light was better than that under strong sunlight.
出处 《无锡轻工大学学报(食品与生物技术)》 CSCD 北大核心 2003年第5期53-56,共4页 Journal of Wuxi University of Light Industry
关键词 中药 大黄 蒽醌衍生物 成分分析 稳定性 rhubarb anthraquinone derivate rhein substance stability
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参考文献9

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