基于中医传承辅助平台的中医治疗疫球蛋白a肾病组方规律研究

Analysis on Regularities of Recipes for IgA Nephropathy Based on Traditional Chinese Medicine Inheritance Support System

目的:基于中医传承辅助平台2.5版,探究中国期刊全文数据库(CNKI)中当代中医使用中药治疗IgA肾病的组方规律。方法:通过收集CNKI中采用中医方剂治疗IgA肾病的相关文献,建立IgA肾病方剂数据库,使用中医传承辅助平台软件,探索用药规律。结果:CNKI中名老中医治疗IgA肾病方剂共118首,包含中药227种。其中以益气健脾、滋阴清热活血药物使用频率最高,出现频率最高的药物组合为黄芪-茯苓。演化得到核心组合14个,新处方7首。结论:通过中医传承辅助平台对CNKI数据库筛选出的治疗IgA肾病的方剂进行分析,得出组方以清热利咽、滋阴补肾活血为主,同时不忘顾护脾肾。进而揭示组方规律,为临床治疗提供参考。

Objective: To investigate the formula of traditional Chinese medicine to treat IgA nephropathy in the China National Knowledge Internet(CNKI) based on the Traditional Chinese Medicine Inheritance Support System(V2.5).Methods: Cases of treating IgA nephropathy with Chinese herbal formulas was enrolled to establish IgA nephropathy prescriptions database and the medication rule was explored by the Traditional Chinese Medicine inheritance software.Results: There were 118 IgA nephropathy prescriptions in CNKI, including 227 traditional Chinese medicines. Among them, the commonly efficacy of traditional Chinese medicine was replenishing qi to invigorate the spleen, nourishing yin to clearing heat, promoting blood circulation and the most frequently couplet medicines was Huangqi-Fuling. The evolution resulted in 14 core combinations and 7 new prescriptions. Conclusion: The law of the medicine combination was revealed to treat IgA nephropathy in CNKI and find the novel prescriptions, and it may provide reference for clinical treatment.