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在押青少年中丙肝病毒感染的发病率和危险因素

Prevalence and risk factors for hepatitis C virus infection among adolescents in detention
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摘要 Objective: To assess the prevalence and correlates of hepatitis C virus infection in a sample of detained adolescents. Design/Setting/ Participants: Cross-sectional prevalence study with 10- to 18- year-old adolescents who were consecutively admitted to a juvenile detention center in San Antonio, Tex. Main Outcome Measures: The prevalence of hepatitis C virus infection and associated risk factors. Results: Of the 1002 participants, 75% were Hispanic and the mean age was 15 years. Twenty adolescents had laboratory data consistent with hepatitis C virus infection, giving an overall prevalence of 2.0% (95% confidence interval, 1.2- 3.1). All adolescents infected with hepatitis C virus were Hispanic (13 boys and 7 girls). Although a high proportion of the participants reported having had intranasal drug use (55.6% ), tattooing (50.5% ), or body piercing (25.3% ), the only factor significantly associated with hepatitis C virus infection was having a history of injection drug use. Injection drug use was reported by 5.3% of the participants but by 95% (19/20) of those infected with the hepatitis C virus. Conclusions: This study indicates that injection drug use was linked with the majority of hepatitis C virus infections in this population of detained adolescents, similar to findings in adults. These adolescents reported a high frequency of other behaviors that could potentially pose a risk for contracting bloodborne infections. Effective prevention and awareness programs in a detention setting need to be comprehensive and include screening, hepatitis A and B immunizations, and risk-red-uction counseling. Objective: To assess the prevalence and correlates of hepatitis C virus infection in a sample of detained adolescents. Design/Setting/ Participants: Cross-sectional prevalence study with 10- to 18- year-old adolescents who were consecutively admitted to a juvenile detention center in San Antonio, Tex. Main Outcome Measures: The prevalence of hepatitis C virus infection and associated risk factors. Results: Of the 1002 participants, 75% were Hispanic and the mean age was 15 years. Twenty adolescents had laboratory data consistent with hepatitis C virus infection, giving an overall prevalence of 2.0% (95% confidence interval, 1.2- 3.1). All adolescents infected with hepatitis C virus were Hispanic (13 boys and 7 girls). Although a high proportion of the participants reported having had intranasal drug use (55.6% ), tattooing (50.5% ), or body piercing (25.3% ), the only factor significantly associated with hepatitis C virus infection was having a history of injection drug use. Injection drug use was reported by 5.3% of the participants but by 95% (19/20) of those infected with the hepatitis C virus. Conclusions: This study indicates that injection drug use was linked with the majority of hepatitis C virus infections in this population of detained adolescents, similar to findings in adults. These adolescents reported a high frequency of other behaviors that could potentially pose a risk for contracting bloodborne infections. Effective prevention and awareness programs in a detention setting need to be comprehensive and include screening, hepatitis A and B immunizations, and risk-red-uction counseling.
机构地区 Indiana University
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