基于文献计量分析的3种药用甘草的研究现状

Research Status and Trends of Three Kinds of Medical Radix Glycyrrhizae Based on Bibliometric Analysis( 1992-2018)

目的:为深入了解3种药用甘草相关研究的全球状况和前沿动态,客观反映相关研究国家、机构和个人在该研究方面的科学能力和影响力。方法:选取Web of Science TM核心合集数据库为数据源,利用Citespace分析软件,对1992—2018年3种药用甘草的研究论文进行文献计量分析。结果:共检索文献2 092篇,对于3种药用甘草的研究主要集中在医学和理学方面,具体学科为药理学/药剂学(30. 31%)、化学(24. 45%)、生物化学/分子生物学(16. 16%);以高频关键词进行共词分析,得到3种药用甘草的研究热点。结论:研究分为2个阶段,第一阶段(1992—2003)主要是对甘草根中黄酮类和酚类化合物进行研究,第二阶段(2004至今)集中在化学成分的提取分离、主要活性成分的药理作用与基因的表达等方面,目前仍处于第二阶段。

Objective: In order to deeply understand the global status and cutting-edge dynamics of the research on 3 kinds of medical Radix Glycyrrhizae,and to objectively reflect the scientific capabilities and influence of relevant research countries,institutions and individuals in this research. Methods: Using the Web of Science TM core collection database as the data sources,and Citespace as analysis sofeware. A bibliometric analysis of research papers on 3 kinds of medical Radix Glycyrrhizae from 1992 to 2018 was made. Results: A total of 2092 papers were found. These papers mainly focused on the medical and scientific research,especially pharmacology or pharmaceutics( 30. 31%),chemistry( 24. 45%),biochemistry or molecular biology( 16. 16%). Analysis of keywords with high frequency showed research hotspots in these 3 kinds of Radix Glycyrrhizae. Conclusion: The current research of these 3 kinds of Radix Glycyrrhizae can be divided into 2 phases. The first phase( 1992-2003) mainly studied flavonoids and phenolic compounds in licorice root. The second stage( 2004-present) focused on the extraction and separation of chemical components,the pharmacological action of major active ingredients and the expression of genes,etc. We are still in the second stage.