燥湿化痰补肾活血方联合克罗米芬治疗痰湿阻滞型多囊卵巢综合征所致不孕症临床观察

Clinical Observation on Cangfudaotan Decoction Combined with Clomifene in Treating PCOS Patients with Non-Ovulation Infertility of Phlegm-damp Stagnation Type

目的研究燥湿化痰补肾活血方联合克罗米芬治疗痰湿阻滞型多囊卵巢综合征不孕症的临床疗效。方法将60例痰湿阻滞型多囊卵巢综合征不孕症患者随机分为治疗组和对照组各30例。对照组使用克罗米芬治疗,治疗组在对照组治疗手段基础上,加用燥湿化痰补肾活血方,监测两组患者子宫内膜厚度、周期排卵率、妊娠率、体重指数,比较两组治疗总有效率。结果治疗组总有效率83.3%,高于对照组63.3%,差异有统计学意义(P<0.05),且治疗后子宫内膜厚度、妊娠率、体重指数等指标均显著好于对照组,差异有统计学意义(P<0.05)。结论对于痰湿阻滞型多囊卵巢综合征不孕症患者,在常规克罗米芬治疗基础上联合应用燥湿化痰补肾活血方疗效显著,值得临床推广应用。

Objective To investigate the clinical effects of Cangfudaotan decoction combined with clomifene in treating PCOS patients with non- ovulation infertility of phlegm- damp stagnation type. Methods Sixty cases of PCOS patients with non- ovulation infertility of phlegm- damp stagnation type were randomly divided into treatment group and control group. The control group applied clomiphene therapy,while the treatment group gave patients Cangfudaotan decoction combined with clomifene. Endometrial thickness,cycle ovulation rate,pregnancy rate,body mass index and total effective rate of the two groups were monitored and measured for comparison. Results The effective rate of treatment group was 83. 3%,which was higher than that of the control group( 63. 3%),and the difference was statistically significant( P < 0. 05). Compared with the control group,the endometrial thickness and pregnancy rate and body mass index in the treatment group were significantly higher,and the differences were statistically significant( P < 0. 05). Conclusion For the PCOS patients with non- ovulation infertility of phlegm- damp stagnation type,Cangfudaotan decoction combined with clomifene has significant clinical effects,which is worthy of clinical application.