康莱特联合支气管动脉灌注栓塞治疗肺癌的临床研究

Clinical Research of Kang Lai Te With Bronchial Arterial Perfusion Embolization for the Treatment of Lung Cancer

目的观察康莱特联合支气管动脉灌注栓塞治疗肺癌的临床效果。方法回顾性观察64例肺癌患者,并以同期肺癌患者68例为对照组,两组均给予支气管动脉灌注栓塞治疗,治疗组另给予静注康莱特注射液,观察两组的总有效率、临床疗效、生存率、生活质量改善情况、不良反应。结果治疗组总有效率明显高于对照组,临床疗效治疗组优于对照组,差异有统计学意义(P<0.05);治疗组的6个月、1年、3年生存率高于对照组,差异有统计学意义(P<0.05);对照组生活质量改善情况观察组优于对照组,差异有统计学意义(P<0.05);治疗组不良反应明显低于对照组,差异有统计学意义(P<0.05)。结论康莱特联合支气管动脉灌注栓塞治疗肺癌临床效果显著,毒副作用小,值得推广。

Objective To observe the clinical effect of Kang Lai Te with bronchial arterial perfusion embolization for treatment lung cancer. Methods Patients with lung cancer were put into treatment group( n= 64) with retrospective observation and control group( n = 68). Patients in two groups were given bronchial artery perfusion embolization. Patients in the treatment group was given another Kang- Lai- Te injection.Then we observed the total effective rate,clinical curative effect,survival rate,improvement about life quality and adverse reaction of two groups. Results Total effective rate of treatment group was 84. 38%,which was significantly higher than the 67. 65% of the control group( P < 0. 05). Clinical efficacy of the treatment group was better than that of control group( P < 0. 05). The survival rate of 6 month,one year and three year in treatment group were both higher than the control group( P < 0. 05). The patients in treatment group obviously improved their quality of life to the control group( P < 0. 05). The toxic and side effect of patients in treatment group was lower than the control group( P < 0. 05). Conclusion Treatment effect of Kang- Lai- Te with bronchial arterial perfusion embolization treating lung cancer is remarkable. It has small side effects and is worthy of promoting.