肥胖与非肥胖患者患睡眠呼吸暂停综合征的危险因素分析

Analysis on the Risk Factors of Sleep Apnea Syndrome in the Patients with / without Obesity

目的探索分析不同性别肥胖与非肥胖人群患阻塞性睡眠呼吸暂停综合征(OSA)的相关危险因素。方法对行多导睡眠检测的229位男性患者和127位女性患者采集相关数据,包括体质指数(BMI)、颈围、臂围、腰围、臀围、腰臀比、年龄、睡眠呼吸暂停低通气指数(AHI)等。根据性别和BMI分组,按BMI分为肥胖组(BMI≥28),非肥胖组(BMI<28)。对所收集数据与是否患睡眠呼吸暂停(AHI≥5)进行相关性统计分析,寻找不同性别肥胖与非肥胖组患者患睡眠呼吸暂停的危险因素。结果男性患者中,肥胖患者患OSA的危险因素有,腰围、腰臀比、腰围身高比,多元回归分析后,腰围身高比与患OSA有关;非肥胖的男性患者患OSA的危险因素有颈围、年龄。女性患者中,肥胖患者患OSA的危险因素有颈围、腰围、年龄。非肥胖女性患者尚未找到危险因素。结论不同性别肥胖与非肥胖患者患OSA的危险因素是不同的,肥胖是OSA的一个重要因素,但不能代表全部患者,应关注非肥胖的患者。

Objective To explore the relevant risk factors of obstructive sleep apnea syndrome( OSAS) in the patients of either gender with / without obesity. Methods The multi- conductive sleep monitoring was adopted to collect the relevant data among 229 male patients and 127 female patients,including body mass index( BMI),neck circumference( NC),arm circumference( AC),waist circumference( WC),hip circumference( HC),waist- hip ratio( WC / HC),age,apnea hypopnea index( AHI) etc. According to the gender and BMI,the obesity group( BMI≥28) and the non- obesity group( BMI < 28) were divided. The correlative statistical analysis was done on all of the data and the condition of OSAS( AHI≥5) and the risk factors of OSAS were explored in the patients of either gender with / without obesity. Results Among the male patients,the risk factors of obese males were HC,WC / HC and WC / height. It was found after multiple regression analysis that WC / height ratio was relevant with OSAS. The risk factors of non- obese males were NC and age. Among the female patients,the risk factors of obese females were NC,WC and age. The risk factors in the non- obese females were not found. Conclusion The risk factors of OSAS are different among the patients of either gender with / without obesity. Obesity is the major factor of OSAS,but it cannot represent all of the patients. The patients without obesity should be considered greatly in OSAS.