复方甘草酸苷注射液联合丹参粉针治疗慢性乙肝肝纤维化的疗效观察

Efficacy Observation of Liver Fibrosis in Chronic Hepatitis B Treated with Compound Glycyrrhizin Injection and Salvia Miltiorrhiza Power Injection

目的观察复方甘草酸苷注射液联合丹参粉针治疗乙肝肝纤维化的临床疗效。方法将48例乙肝肝纤维化患者采用数字表法随机分为对照组与治疗组,每组24例。对照组给予复方甘草酸苷注射液,治疗组在对照组的基础上加用丹参粉针注射液。比较两组患者治疗后临床疗效、临床症状及肝功能、肝纤维化指标变化情况。结果两组患者治疗后,治疗组患者临床疗效、临床症状、肝功能及肝纤维化指标改善情况均明显优于对照组,两组比较,差异有统计学意义(P<0.05)。结论复方甘草酸苷注射液联合丹参粉针治疗乙肝肝纤维化疗效显著,值得临床推广应用。

Objective To observe the clinical efficacy on liver fibrosis in chronic hepatitis B treated with compound glycyrrhizin injection and salvia miltiorrhiza power injection. Methods Forty- eight patients of liver fibrosis in chronic hepatitis B were divided into a control group and a treatment group,24 cases in each one according to the random number table. In the control group,compound glycyrrhizin injection was used. In the treatment group,on the basic treatment as the control group,salvia miltiorrhiza power injection was added. The clinical efficacy,clinical symptoms,liver functions and the indicators of liver fibrosis were compared in the patients between the two groups. Results After treatment,the improvements in the clinical efficacy,clinical symptoms,liver functions and the indicators of liver fibrosis in the treatment group were all apparently better than those in the control group,presenting the significant difference( P < 0. 05). Conclusion The combination of compound glycyrrhizin injection and salvia miltiorrhiza power injection achieves the significant efficacy and deserves to be promoted in clinical practice.