摘要
药物控制释放是目前十分活跃的研究领域,因为它具有长效、高效、靶向、低副作用等特点,因此具有智能开关的环境感应式控制释放膜成了目前膜学与医用高分子材料的研究热点。文中基于大量研究文献,主要综述了温度感应型、pH感应型以及葡萄糖浓度感应型等环境感应式控制释放开关膜的研究进展。
Controlledrelease drug delivery system is one of the most active fields of research and development at present, because of its advantages such as longterm, highefficiency, targeting and low byeffects. Environmental stimuliresponsive controlledrelease membranes with functional gates are getting more and more attentions in the fields of membrane science and medical macromolecular materials. On the basis of a large quantity of references on this topic, a review was made on the developments of environmental temperatureresponsive type, pHresponsive type and glucoseresponsive type controlledrelease gating membranes.
出处
《高分子材料科学与工程》
EI
CAS
CSCD
北大核心
2003年第5期37-41,共5页
Polymer Materials Science & Engineering
基金
国家自然科学基金(20206019)
国家教育部留学回国人员科研基金
四川大学振兴计划142人才基金
四川大学青年科学研究基金资助项目
关键词
环境感应式
控制释放
开关膜
研究进展
药物控制释放
接枝法
扩散透过率
environment-responsive
controlled-release
gating membrane
grafting polymerization
diffusional permeability
research progress
