分子蒸馏技术纯化辣椒碱类物质的工艺条件优化

Optimization of Conditions for Purification of Capsaicinoids by Molecular Distillation

以刮膜式分子蒸馏装置对辣椒碱的纯化工艺条件进行研究,考察蒸馏温度、真空度、刮膜转速对辣椒碱纯化效果的影响;在单因素试验基础上采用三因素三水平Box-Behnken设计进行响应面优化分析,得到辣椒碱类物质的优化工艺条件为蒸馏温度170℃、真空度0.15 mbar、刮膜转速400 r/min,在此条件下辣椒碱类物质的质量分数由0.001 5%提高到13.11%。

Wiped-film molecular distillation was used to purify capsaicinoids from chili pepper. The effects of distillation pressure, wiper rotation speed and distillation temperature on capsaicinoid purity were studied. Base on single-factor experiments, a three-factor, three-level Box-Behnken design was carried out for the optimization of these three parameters by response surface analysis. The optimized purification conditions were obtained as follows: 170 ℃, 0.15 mbar and 400 r/min for distillation temperature, vacuum degree and wiper rotation speed, respectively. As a result, the purity of capsaicinoids was increased from 0.001 5% to 13.11%.