摘要
为弄清下关生沱茶(Xiaguan raw Tuocha,XRT)的成分和其体内胃损伤预防效果,本实验利用LC-MS和细胞因子分析,同时还测定了胃液量和胃液的pH值。结果表明:XRT具有12种成分,这些成分使XRT具有胃损伤预防效果。高质量浓度的XRT相比低质量浓度的XRT,细胞因子IL-6和TNF-α下降。1000mg/kg的XRT处理时小鼠显示出和正常小鼠接近的低胃液量(2.0mL)和高的pH值(3.1)。由此可知,下关生沱茶包含很多功能性成分并且表现出强有力的胃损伤预防效果。
Xiaguan Tuocha is a functional drink and known to possess some health properties. In order to identify the chemical components and investigate preventive effects of Xiaguan raw(unfermented) Tuocha(XRT) on gastric injury in vivo, liquid chromatography-mass spectrometry(LC-MS) and cytokine analysis were used in this study, and the gastric secretion and pH of gastric juice were also tested. Twelve components were found in XRT, all of which contributed to the preventive effect on gastric injury. XRT at higher concentration reduced the levels of serum proinflammatory cytokines such as IL-6 and TNF-α compared with at lower concentration. The 1 000 mg/kg XRT showed the best inhibitory effect on gastric injury(78.7% inhibitory rate). The 1 000 mg/kg XRT treated rats also exhibited similarly low gastric secretion(2.0 mL) and higher pH of gastric juice(pH 3.1) compared with normal rats. Xiaguan Tuocha contained many functional components and exerted a strong preventive effect on gastric injury.
出处
《食品科学》
EI
CAS
CSCD
北大核心
2014年第13期271-275,共5页
Food Science
基金
重庆市高校创新团队建设计划项目(KJTD201325)
重庆第二师范学院引进高层次人才科研启动费基金项目
